ABSTRACT
Objectives: the aim of this study was to evaluate the effect of different denture cleansing methods on microorganisms and surface roughness of acrylic resin both invivo and invitro
Material and methods: one hundred and eleven discs were used. Thirty six discs were chosen for the roughness evaluation and a further seventy five for the microbiological test. For the invivo evaluation, thirty six patients who were wearing their dentures for more than one year were selected. Three types of cleansers were evaluated; electric toothbrush as a mechanical method, effervescent tablets as a chemical immersion and propolis as a natural immersion, and water was used as control. In vitro cleansing of discs simulated one year of cleansing. Surface roughness was measured with profilometer, invivo and invitro microorganisms count were evaluated before and after cleansing. Correlation between roughness and microorganisms count was done
Results: the three types of cleansers showed significant effect on roughness and on microorganisms invivo and invitro. There was highly significant difference after cleansing between the 4 groups regarding roughness [F= 41.51, P= 0.000], invivo bacterial count [F= 19.487, P= 0.000] and fungal count [F= 6.666, P= 0.001]
Conclusion: the effect of propolis and effervescent tablets on microorganisms was comparable and they were more effective than the brush method. However, Propolis was found with a powerful antimicrobial effect against most oral microorganisms, and can be used on prescription as a denture soak with equivalent or higher effect as a cleanser especially with its advantage as a promising natural product
ABSTRACT
Difference in the composition of microbiota in different periodontal diseases has been observed. There are several microbial methods used to identify the periodontopathic bacteria which harbor the periodontally affected sites. The present study compared molecular detection of bacterial periodontitis to conventional microbiological method as well as identifying prominent isolated species. This study also describes clinical parameters as well as evaluating the effect of non-surgical treatment modalities [SRP] among different periodontal diseases on total viable bacterial count. Clinical parameters include: probing depth [PD], clinical attachment level [CAL], bleeding on probing percent [BOP%] at baseline and three months after. Gingival crevicular fluid samples from 45 patients were collected and analyzed at day 0, 1, 30 and 90 days after SRP' treatment. The microbiologic assessment was done using universal primers for PCR detection of bacterial periodontal infection. The ability to detect bacterial infection from 45 gingival crevicular fluid samples by PCR using universal primers encoding for the 16 S rDNA was compared with bacterial culture. Bacteria were detected by PCR with 100% specificity and 77.5% sensitivity compared to culture. Detection of 16 S rDNA proved to be effective in preventing PCR inhibition and was applied to detect the occurrence of non-cultural bacteria in the tested samples. The occurrence of bacteria was decreased by non-surgical mechanical debridement [SRP] which was evaluated by total viable count technique. Frequently isolated bacteria species were identified as Porpheromonas gingivitis, Fusobacterium nucleatum, Tenner Ella forsythia, Aggregibacter actinomyctemecommitans and Prevotella intermedia. The results indicated that using universal bacterial primers is a rapid and simple method for detection of bacterial periodontitis. A favorable clinical response to these therapeutic measures can be obtained. Moreover, the bacterial count is affected significantly by non- surgical treatment modality
ABSTRACT
Pre-term labor often results in pre-term birth Previous studies have suggested that periodontal disease may be an important risk factor for pre-term low-birth weight. The aim of the present study was to evaluate the association between periodontal clinical parameters, CRP and IL-6 levels in sera of Egyptian pregnant women suffering from pre-term labor. One hundred and twenty-five women were enrolled in this study. Systemic conditions were assessed and serum CRP was evaluated. The women were divided into two groups: group I CRP-positive and group II CRP-negative. Serum IL-6 was also evaluated. Periodontal examination included gingival index [GI], probing depth [PD] and clinical attachment loss [CAL]. Gestational age, parity, gravidity, cervical dilation and cervical length, were also recorded. On comparing both groups , there was a statistical significant increase in GI, PD, CAL and serum IL-6 levels in favor of CRP-positive pregnant women. Positive significant correlations were found between all parameters and CAL. Moreover, there was a positive correlation between age and probing depth in CPR-positive pregnant women. In conclusion, preterm Pre-term labor women with positive CRP revealed worsened periodontal conditions and elevated serum IL-6 levels compared to CRP-negative women. The elevated levels of serum CRP and IL-6 could have affected the maintenance of proper uterine-fetus relationship, resulting in premature uterine contractions
ABSTRACT
Sonography and computed tomography play complimentary roles in imaging lesions of the salivary glands. The present investigation was carried out to evaluate the role of high frequency ultrasonography [HF US] and computerized tomography [CT] in the diagnosis of salivary gland lesions .Moreover, the diagnosis was confirmed by histopathological examination. Fourteen patients suffeingr from swelling and/ or pain of one of the major salivary gland were referred from the out patient dental clinic in Alzhraa hospital. Clinical and radiological examinations. HF US andCT were carried out for all patients and it seems that the two techniques are equally effective. Therefore, HF US can replace CT, as it is non-invasive technique and less expensive. Doppler US gives more information about intra and prelesional vascularaization and soft tissue component surrounding the blood vessels
ABSTRACT
The goal of this study was to compare the results obtained from the combination of bio-absorbable collagen membrane and Platelet -Rich Plasma [PRP] under coronally advanced flap and the use of bioabsorbable collagen membrane under coronally advanced flap alone in the treatment of recession. Moreover, to evaluate the effect of the two treatment modalities on the clinical results
Methods: Fifteen female systemically healthy patients participated in this study. They suffered from two gingival recessions Miller's Class I. A split mouth design was chosen to be performed. These patients received a bioabsorbable collagen membrane and Platelet -Rich Plasma [PRP] under coronally advanced flap on one site [group I] and a bioabsorbable collagen membrane under a coronally advanced flap alone on the other site [group II]. Baseline clinical parameters included recession depth [RD], recession width [RW], Probing depth [PD], and Clinical attachment level [CAL], gingival index [GI], wound healing index [WHI]. Patients were followed up for 24 weeks post surgery
Results: Fifteen patients with thirty gingival recession defects. The RD at 24 weeks were significantly reduced from 4.47 +/- 0.64 mm to 0.40 +/- 0.51mm in group I and from 4.53 +/- 0.52mm tol.27 +/- 0.70 in group II [P <0.0004]. The mean root coverage [RC] was 91,67% +/- 10.63 in group I and 73.00% +/- 13.60 in group II. In group I 60% of sites experienced total root coverage [ie. 100% root coverage at the 24- week postoperative follow-up]
Conclusion: The combined use of PRP and collagen membrane under CAP for root coverage procedure may provide an enhancement on the final clinical therapeutic outcomes in the treatment of Miller's Class I recession defects
ABSTRACT
Systemic Lupus Erythematosus [SLE] is an autoimmune disease commonly occurs in of childbearing age, with connective tissue inflammation particularly joints and causes characteristic rashes
Subjects and Methods: the present study includs30 premenopausal females, they were divided into 3 groups. Group I consists o ten premenopausal females without SLE, Group II include ten premenopausal females had SLE,disease duration less than three years, Group III include ten premenopausal females had SLE, disease duration more than three years. Bone mineral density [BMD] in the heel of right foot by Achilles Express in all groups had been performed. Estimation of the serum level of Dehydroepiandrosterone Sulphate [DHEA-S] hormone and serum level of calcium, phosphorous, sodium and potassium
Results: the results of the present study showed that in group II the BMD was 10% with osteoporotic, 40% with osteopenic and 50% with normal BMD, group III the BMD was 10% with osteoporotic, 60% with osteopenic and 30% with normal BMD. The correlations were done between BMD and serum minerals calcium, phosphorous, sodium and potassium in SLE patients [Group II and III]. Statistically high significant increase was found among osteopenic versus control women. Moreover a significant increase of serum calcium and sodium while there was a significant decrease in serum DHEA-S, phosphorous and potassium
Conclusions: there is a relationship between level of DHEA and the progression of SLE. Moreover there is relation between the decline in serum levels of DHEA-S and phosphorous, and the elevation of serum levels of calcium and the occurrence of osteoporosis in SLE. Treatment with DHE is beneficial in controlling of the disease activity in LES patients
ABSTRACT
The present study was designed to evaluate the effect of some antidiabetic plants on the hematological parameters in aloxan induced diabetes in albino rats
Eighty adult albino rats [120- +/- 20 gm b.wt] were randomly divided into eight groups ten on each group, the first group conserved as control group. The remaining rats were injected with alloxan to induce diabetes. The second group conserved as diabetic group. The third group was diabetic rats treated with a mixture consists of Nigella Sativa, Aloe Vera, Ferula assa-foetida , Boswelli Carteri, Commiphora Myrrha. [0.1ml/100gm b.wt]
Fourth group treated with 0.1ml/100gm b.w of Nigella Sativa, Fifth group treated with 0.05ml/100gm b.w of Aloe Vera,Sixth group treated with 0.1ml/100gm b.w of Ferula assa-foetida, Seventh group treated with 0.1ml/100gm b.w of Boswelli Carteri, Eighth group treated with 0.1ml/100gm b.w of Commiphora Myrrha. Haematological parameters includes: red blood cell count [RBCs], hemoglobin concentration [Hb], hematocrit value [Hct%], total and differential white blood cell cont [WBCs] were done after 30 days of treatment and after 15 days of recovery period
The result of RBCs count, Hb concentration and Hct value were significantly decreased in diabetic, Nigella Sativa and Aloe Vera treated groups, throughout the experiment, except Aloe Vera treated group showed insignificant change after the recovery period.while insignificant changes was recorded in the remnant groups during the experimental period
WBCs count, lymphocyte and neutrophil percentage were highly significant increased in diabetic and Ferula assa-foetida treated rats after treatment and recovery periods. While insignificant differences were observed in the other treated groups. Moreover, no significant changes were recorded in eosinophils and monocytes in all groups throughout the study period
Diabetes mellitus in experimental animal can be treated with some plants which have antidiabetic effect, the present investigation was designed to illustrate any hazard effect of these plants on some hematological parameter. Further investigations on each plant and their mixture are needed to role out its effect on both diabetes and the vital parameters
ABSTRACT
The accuracy of diagnostic modalities that are currently used to evaluate TMJ disorders is equivocal. Magnetic resonance imaging MRI is the gold standard for disc position identification purposes. However, its availability and cost-effectiveness may be problematic. Ultrasonography US is widely available and cost effective. The purpose of the present study is to determine the efficacy of MRI with emphasis oil coronal sections as well as US in the diagnosis of TMJ derangement
Material and Methods: Twenty patients with a recent history of TMJ locking in one or both joints were the subject of this study. Clinical examination was carried out prior to MRI and US
Conclusion: Our data support reports in the literature that routine use of coronal sections together with sagittal sections during MR imaging is extremely advantageous. We recommend the use of US as an adjunct to other diagnostic modalities for TMJ imaging
ABSTRACT
This article reports two clinical modalities of treatment for class II B/C furcation defects. Twenty two mandibular molar teeth demonstrating class II furcation [with severe bone loss around one root] were included in the study. The therapy selected entailed scaling and root planning, removal of any carious lesions or leaking restorations .Out of the twenty two furcation defects eleven were managed with hemisection/root resection after reciving proper endodontic treatment prior the resection. The other furcation defects were treated with regenerative therapy -tricalcium phosphate alloplast was packed into the defect followed by collagen membrane placement over the graft. The results revealed significant improvement as regard all the recorded clinical parameters along the non-resected root in root resection group [RR]. With regenerative therapy promising clinical results were achieved in guided tissue regeneration and graft group[GTR and graft] with significant reduction in pocket depth and gain inclinical attachment level. Re.-entery procedure at 9 months showed favourable osseous changes with insignificant difference between the two groups. The only clinical parameter in which significant difference was demonstrated between groups was the gingival recession. Marked gingival recession was detected in RR group. Since long term prognosis of resected teeth is problematic and progressive gingival recession complicate the procedure, an alternative treatment modality has to be evaluated and compared to the resective techniques. In conclusion, the results of the present study showed that root resection is a good therapeutic modality for saving teeth but if the regenerative therapy is rendered, periodontally involved molars can be maintained and serve successfully instead of utilizing resective techniques So specific periodontal .endodontic and restorative factors must be taken into consideration whenever root resection has been attempt to be performed
ABSTRACT
The aim of the present study was to determine interleukjn-6 [IL-6] levels in gingival crevicular fluid [GCF] and serum and to compare the levels with clinical periodontal findings in patients with diabetes mellitus [DM] and chronic periodontitis [CP]. A total of 30 patients were divided into 3 groups [10 patient with DM and CP, 10 patients with CP and 10 healthy controls] Gingival index [GI] and pocket dopth [PD] values for each CP patients were recorded. Enzyme linked immunosorbent assay for quantitative detection of IL-6 in each GCF and serums sample was employed. Significant difference was detected between all groups with the lowest level of GCF IL-6 in DM/CP. However various IL-6 levels were detected in the serum of DM/CP group which failed to be assayed for CP and control group. No strong correlation could be detected between GCF IL-6 level and GI score or PD values. The finding of the present study suggests that IL-6 should not be considered as just an inflammatory mediator aiding in tissue destruction but it posses a pivotal role in tissue homeostasis To our knowledge this study is the first report correlating IL-6 levels in insulin dependent diabetes mellitus to their clinical periodontal data